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The Big Scream begins with Invisible Man, given the name Dr. Henry Davenport, giving an explanation of the events that had happened. He, Big Ed (The Monster), Wolfmon (Werewolf), and Mummy were guards at theMonster Mountain prison, which kept several monsters, including Tyrannosaurus Rex and Cyclops. However,Vampire had a plot to shrink himself down so he could escape the prison. It ended up shrinking the entire mountain and blowing it to California. There, Dr. Davenport and the others found Carrie Raven, daughter of a famous horror writer, and befriended her.